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Int. J. Environ. Res. Public Health 2017, 14(4), 417;

One-Year Results of a Synthetic Intervention Model for the Primary Prevention of T2D among Elderly Individuals with Prediabetes in Rural China

Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Changsha 410078, China
Department of Preventive Medicine, Medical School, Hunan University of Chinese Medicine, Changsha 410208, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Li Ming Wen
Received: 19 January 2017 / Revised: 31 March 2017 / Accepted: 10 April 2017 / Published: 14 April 2017
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Objective: The objective of this study was to evaluate the effectiveness of a synthetic intervention model aimed at preventing type 2 diabetes and controlling plasma glucose, body weight and waist circumference in elderly individuals with prediabetes in rural China. Methods: We randomly assigned 434 (180 men and 254 women; mean age, 69 years; mean body mass index, 23.6 kg/m2) with prediabetes to either the intervention group or the control group. Each participant in the intervention group received synthetic intervention for 1 year. Results: The incidence of diabetes was 4.2% in the intervention group, versus 19.7% in the control group at the end of 1 year (p < 0.001). Compared with the control group, the intervention group experienced a great decrease in fasting glucose (−3.9 vs. 2.2 mg/dL, p < 0.001), body weight (−3.2 vs. 1.7 kg, p < 0.001), waist circumference (−2.4 vs. 1.0 cm, p < 0001), total cholesterol (−9.1 vs. −4.6 mg/dL. p = 0.014) and HbA1c (−1.0 vs. 0.1 mg %, p = 0.002) at the end of 1 year. Conclusions: The incidence of diabetes of the control group was higher than that of the intervention group. Besides, the synthetic intervention contributes to weight loss and glucose decrease, and may be effective in reducing the risk of diabetes among elderly individuals with prediabetes in rural China. View Full-Text
Keywords: pre-diabetes; intervention; physical activity pre-diabetes; intervention; physical activity

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Hu, Z.; Qin, L.; Xu, H. One-Year Results of a Synthetic Intervention Model for the Primary Prevention of T2D among Elderly Individuals with Prediabetes in Rural China. Int. J. Environ. Res. Public Health 2017, 14, 417.

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