Endocrine Disruptors Leading to Obesity and Related Diseases
AbstractThe review aims to comprehensively present the impact of exposure to endocrine disruptors (EDs) in relation to the clinical manifestation of obesity and related diseases, including diabetes mellitus, metabolic syndrome, cardiovascular diseases, carcinogenesis and infertility. EDs are strong participants in the obesity epidemic scenery by interfering with cellular morphological and biochemical processes; by inducing inflammatory responses; and by presenting transcriptional and oncogenic activity. Obesity and lipotoxicity enhancement occur through reprogramming and/or remodeling of germline epigenome by exposure to EDs. Specific population groups are vulnerable to ED exposure due to current dietary and environmental conditions. Obesity, morbidity and carcinogenicity induced by ED exposure are an evolving reality. Therefore, a new collective strategic approach is deemed essential, for the reappraisal of current global conditions pertaining to energy management. View Full-Text
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Petrakis, D.; Vassilopoulou, L.; Mamoulakis, C.; Psycharakis, C.; Anifantaki, A.; Sifakis, S.; Docea, A.O.; Tsiaoussis, J.; Makrigiannakis, A.; Tsatsakis, A.M. Endocrine Disruptors Leading to Obesity and Related Diseases. Int. J. Environ. Res. Public Health 2017, 14, 1282.
Petrakis D, Vassilopoulou L, Mamoulakis C, Psycharakis C, Anifantaki A, Sifakis S, Docea AO, Tsiaoussis J, Makrigiannakis A, Tsatsakis AM. Endocrine Disruptors Leading to Obesity and Related Diseases. International Journal of Environmental Research and Public Health. 2017; 14(10):1282.Chicago/Turabian Style
Petrakis, Demetrios; Vassilopoulou, Loukia; Mamoulakis, Charalampos; Psycharakis, Christos; Anifantaki, Aliki; Sifakis, Stavros; Docea, Anca O.; Tsiaoussis, John; Makrigiannakis, Antonios; Tsatsakis, Aristides M. 2017. "Endocrine Disruptors Leading to Obesity and Related Diseases." Int. J. Environ. Res. Public Health 14, no. 10: 1282.
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