Polyethyleneimine Capped Silver Nanoclusters as Efficient Antibacterial Agents
AbstractDevelopment of efficient antibacterial agents is critical for human health. In the present study, we investigated the antibacterial activity of polyethyleneimine (PEI)-capped silver nanoclusters (PEI-AgNCs), based on the fact that nanoclusters normally have higher surface-to-volume ratios than traditional nanomaterials and PEI itself has a strong antimicrobial capacity. We synthesized stable silver nanoclusters by altering PEI molecular weight from 0.6 kDa to 25 kDa and characterized them by UV-Vis absorption and fluorescence spectroscopy and high resolution transmission electron microscopy. The sizes of AgNCs were around 2 nm in diameter and were little influenced by the molecular weight of PEIs. The antibacterial abilities of the four PEI-AgNCs were explored on agar plate and in liquid systems. Our results revealed that the antibacterial activity of PEI-AgNCs is excellent and the reduction of PEI molecular weight could result in the increased antibacterial capacity of PEI-AgNCs. Such proposed new materials might be useful as efficient antibacterial agents in practical clinical applications. View Full-Text
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Xu, D.; Wang, Q.; Yang, T.; Cao, J.; Lin, Q.; Yuan, Z.; Li, L. Polyethyleneimine Capped Silver Nanoclusters as Efficient Antibacterial Agents. Int. J. Environ. Res. Public Health 2016, 13, 334.
Xu D, Wang Q, Yang T, Cao J, Lin Q, Yuan Z, Li L. Polyethyleneimine Capped Silver Nanoclusters as Efficient Antibacterial Agents. International Journal of Environmental Research and Public Health. 2016; 13(3):334.Chicago/Turabian Style
Xu, Dong; Wang, Qingyun; Yang, Tao; Cao, Jianzhong; Lin, Qinlu; Yuan, Zhiqin; Li, Le. 2016. "Polyethyleneimine Capped Silver Nanoclusters as Efficient Antibacterial Agents." Int. J. Environ. Res. Public Health 13, no. 3: 334.
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