Next Article in Journal / Special Issue
The Ala54Thr Polymorphism of the Fatty Acid Binding Protein 2 Gene Modulates HDL Cholesterol in Mexican-Americans with Type 2 Diabetes
Previous Article in Journal / Special Issue
Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2016, 13(1), 8; doi:10.3390/ijerph13010008

Ethnic Differences in Maternal Adipokines during Normal Pregnancy

Department of Obstetrics and Gynecology, School of Osteopathic Medicine, Rowan University, Two Medical Center Drive, Suite 390, Stratford, NJ 08084, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Mark Edberg, Barbara E. Hayes, Valerie Montgomery Rice and Paul B. Tchounwou
Received: 6 August 2015 / Revised: 3 September 2015 / Accepted: 7 September 2015 / Published: 22 December 2015
View Full-Text   |   Download PDF [1542 KB, uploaded 22 December 2015]   |  

Abstract

Two adipokines (adiponectin and resistin) have opposite relations with insulin resistance and inflammation. Our major focus was to determine whether there were detectable ethnic differences in maternal adipokines during pregnancy. We also explored the correlation of the adipokines with maternal glucose homeostasis, blood pressure and anthropometric parameters. Pregnant women (n = 1634) were from a large prospective cohort study in Camden NJ (African-American 36.8%; Hispanic 47.6%; Caucasian 15.6%). Serum adiponectin and resistin were measured at entry (week 16.8) and the 3rd trimester (week 30.7) using the Luminex xMapTechnology. Significant differences were observed among ethnic groups, controlling for confounding variables. African American women were exceptional in that they had decreased adiponectin and increased resistin throughout the course of pregnancy (p < 0.05 to p < 0.0001) and a greater than two fold risk of simultaneously exhibiting low adiponectin (lowest tertile) and high resistin (highest tertile) compared to Caucasians and/or Hispanics. The cohort as a whole and each ethnic group showed similar negative correlations between adiponectin, and glucose homeostasis, blood pressure and anthropometric parameters but there was lesser correspondence with resistin. Our data underscore the need for further research on ethnic variation in adipokines and other physiologic biomarkers during complicated and uncomplicated pregnancy. View Full-Text
Keywords: ethnic difference; adipokine; adiponectin; resistin; normal pregnancy; anthropometric parameters; glucose homeostasis; blood pressure ethnic difference; adipokine; adiponectin; resistin; normal pregnancy; anthropometric parameters; glucose homeostasis; blood pressure
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chen, X.; Scholl, T.O. Ethnic Differences in Maternal Adipokines during Normal Pregnancy. Int. J. Environ. Res. Public Health 2016, 13, 8.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top