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Int. J. Environ. Res. Public Health 2013, 10(12), 6887-6908; doi:10.3390/ijerph10126887
Article

Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database

 and *
Received: 22 September 2013; in revised form: 2 December 2013 / Accepted: 3 December 2013 / Published: 9 December 2013
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Abstract: The human signal-molecule-profiling database (HSMPD) is designed as a prospective medical database for translational bioinformatics (TBI). To explore the feasibility of low-cost database construction, we studied the roadmap of HSMPD. A HSMPD-oriented tool, called “signal-molecule-profiling (SMP) chip” was developed for data acquisition, which can be employed in the routine blood tests in hospitals; the results will be stored in the HSMPD system automatically. HSMPD system can provide data services for the TBI community, which generates a stable income to support the data acquisition. The small-scale experimental test was performed in the hospital to verify SMP chips and the demo HSMPD software. One hundred and eighty nine complete SMP records were collected, and the demo HSMPD system was also evaluated in the survey study on patients and doctors. The function of SMP chip was verified, whereas the demo HSMPD software needed to be improved. The survey study showed that patients would only accept free tests of SMP chips when they originally needed blood examinations. The study indicated that the construction of HSMPD relies on the self-motivated cooperation of the TBI community and the traditional healthcare system. The proposed roadmap potentially provides an executable solution to build the HSMPD without high costs.
Keywords: public health informatics; data acquisition; health data management; signal molecule profiling; lab on a chip public health informatics; data acquisition; health data management; signal molecule profiling; lab on a chip
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Zhao, X.; Dong, T. Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database. Int. J. Environ. Res. Public Health 2013, 10, 6887-6908.

AMA Style

Zhao X, Dong T. Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database. International Journal of Environmental Research and Public Health. 2013; 10(12):6887-6908.

Chicago/Turabian Style

Zhao, Xinyan; Dong, Tao. 2013. "Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database." Int. J. Environ. Res. Public Health 10, no. 12: 6887-6908.



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