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Estimated Fluoride Doses from Toothpastes Should be Based on Total Soluble Fluoride
Department of Paediatric Dentistry and Orthodontics, School of Dentistry, Universidade Estadual de Montes Claros (UNIMONTES), Campus Darcy Ribeiro, Vila Mauricéia, Montes Claros, MG 39410-089, Brazil
Department of Paediatric Dentistry, School of Dentistry, Universidade Federal de Minas Gerais (UFMG), Avenida Antônio Carlos 6627, Belo Horizonte, MG 31270-901, Brazil
Department of Physiological Sciences, Piracicaba Dental School, University of Campinas (UNICAMP), Avenida Limeira 901, Piracicaba, SP 13414-903, Brazil
* Author to whom correspondence should be addressed.
Received: 8 October 2013; in revised form: 23 October 2013 / Accepted: 24 October 2013 / Published: 1 November 2013
Abstract: The fluoride dose ingested by young children may be overestimated if based on levels of total fluoride (TF) rather than levels of bioavailable fluoride (total soluble fluoride—TSF) in toothpaste. The aim of the present study was to compare doses of fluoride intake based on TF and TSF. Fluoride intake in 158 Brazilian children aged three and four years was determined after tooth brushing with their usual toothpaste (either family toothpaste (n = 80) or children’s toothpaste (n = 78)). The estimated dose (mg F/day/Kg of body weight) of TF or TSF ingested was calculated from the chemical analysis of the toothpastes. Although the ingested dose of TF from the family toothpastes was higher than that from the children’s toothpastes (0.074 ± 0.007 and 0.039 ± 0.003 mg F/day/Kg, respectively; p < 0.05), no difference between types of toothpaste was found regarding the ingested dose based on TSF (0.039 ± 0.005 and 0.039 ± 0.005 mg F/day/Kg, respectively; p > 0.05). The fluoride dose ingested by children from toothpastes may be overestimated if based on the TF of the product. This finding suggests that the ingested dose should be calculated based on TSF. Dose of TSF ingested by children is similar whether family or children’s toothpaste is used.
Keywords: fluorides; dentifrices; toothpastes; dental fluorosis; fluorosis risk
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Oliveira, M.J.L.; Martins, C.C.; Paiva, S.M.; Tenuta, L.M.A.; Cury, J.A. Estimated Fluoride Doses from Toothpastes Should be Based on Total Soluble Fluoride. Int. J. Environ. Res. Public Health 2013, 10, 5726-5736.
Oliveira MJL, Martins CC, Paiva SM, Tenuta LMA, Cury JA. Estimated Fluoride Doses from Toothpastes Should be Based on Total Soluble Fluoride. International Journal of Environmental Research and Public Health. 2013; 10(11):5726-5736.
Oliveira, Maria J.L.; Martins, Carolina C.; Paiva, Saul M.; Tenuta, Livia M.A.; Cury, Jaime A. 2013. "Estimated Fluoride Doses from Toothpastes Should be Based on Total Soluble Fluoride." Int. J. Environ. Res. Public Health 10, no. 11: 5726-5736.