Next Article in Journal
An Acetylenic Alkaloid from the Calcareous Sponge Leucetta sp.
Previous Article in Journal
Lobophorin C and D, New Kijanimicin Derivatives from a Marine Sponge-Associated Actinomycetal Strain AZS17
Mar. Drugs 2011, 9(3), 369-381; doi:10.3390/md9030369
Article

Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites

,
,
,
 and *
Received: 4 February 2011; in revised form: 6 March 2011 / Accepted: 18 March 2011 / Published: 21 March 2011
View Full-Text   |   Download PDF [425 KB, uploaded 21 March 2011]   |   Browse Figures
Abstract: Marine invertebrates have proven to be a rich source of secondary metabolites. The growing recognition that marine microorganisms associated with invertebrate hosts are involved in the biosynthesis of secondary metabolites offers new alternatives for the discovery and development of marine natural products. However, the discovery of microorganisms producing secondary metabolites previously attributed to an invertebrate host poses a significant challenge. This study describes an efficient chemical screening method utilizing a 96-well plate-based bacterial cultivation strategy to identify and isolate microbial producers of marine invertebrate-associated metabolites.
Keywords: chemical screening; coral-associated bacteria; UPLC/MS; gorgonian coral chemical screening; coral-associated bacteria; UPLC/MS; gorgonian coral
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Berrue, F.; Withers, S.T.; Haltli, B.; Withers, J.; Kerr, R.G. Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites. Mar. Drugs 2011, 9, 369-381.

AMA Style

Berrue F, Withers ST, Haltli B, Withers J, Kerr RG. Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites. Marine Drugs. 2011; 9(3):369-381.

Chicago/Turabian Style

Berrue, Fabrice; Withers, Sydnor T.; Haltli, Brad; Withers, Jo; Kerr, Russell G. 2011. "Chemical Screening Method for the Rapid Identification of Microbial Sources of Marine Invertebrate-Associated Metabolites." Mar. Drugs 9, no. 3: 369-381.


Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert