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Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo
Key Laboratory of Marine Bio-resources Sustainable Utilization, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China
Guangzhou Jinan Biomedicine Research and Development Center, Guangzhou 510632, China
Department of Biology, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong, China
* Author to whom correspondence should be addressed.
Received: 13 October 2011; in revised form: 14 November 2011 / Accepted: 15 November 2011 / Published: 24 November 2011
Abstract: Five zoanthoxanthin alkaloids (1–5) and four sesquiterpenes (6–9) were isolated from the South China Sea gorgonian Echinogorgia pseudossapo. Their structures were determined on the bases of extensive spectroscopic analyses, including 1D and 2D NMR data. Among them, pseudozoanthoxanthins III and IV (1–2), 8-hydroxy-6β-methoxy-14-oxooplop-6,12-olide (6) and 3β-methoxyguaian-10(14)-en-2β-ol (7) were new, 1 and 3 showed mild anti-HSV-1 activity, and 7 showed significant antilarval activity towards Balanus amphitrite larvae.
Keywords: Echinogorgia pseudossapo; gorgonian; zoanthoxanthin alkaloid; sesquiterpene
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Gao, C.-H.; Wang, Y.-F.; Li, S.; Qian, P.-Y.; Qi, S.-H. Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo. Mar. Drugs 2011, 9, 2479-2487.
Gao C-H, Wang Y-F, Li S, Qian P-Y, Qi S-H. Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo. Marine Drugs. 2011; 9(11):2479-2487.
Gao, Cheng-Hai; Wang, Yi-Fei; Li, Shen; Qian, Pei-Yuan; Qi, Shu-Hua. 2011. "Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo." Mar. Drugs 9, no. 11: 2479-2487.