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Mar. Drugs 2011, 9(11), 2479-2487; doi:10.3390/md9112479

Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo

1 Key Laboratory of Marine Bio-resources Sustainable Utilization, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China 2 Guangzhou Jinan Biomedicine Research and Development Center, Guangzhou 510632, China 3 Department of Biology, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong, China
* Author to whom correspondence should be addressed.
Received: 13 October 2011 / Revised: 14 November 2011 / Accepted: 15 November 2011 / Published: 24 November 2011
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Five zoanthoxanthin alkaloids (15) and four sesquiterpenes (69) were isolated from the South China Sea gorgonian Echinogorgia pseudossapo. Their structures were determined on the bases of extensive spectroscopic analyses, including 1D and 2D NMR data. Among them, pseudozoanthoxanthins III and IV (12), 8-hydroxy-6β-methoxy-14-oxooplop-6,12-olide (6) and 3β-methoxyguaian-10(14)-en-2β-ol (7) were new, 1 and 3 showed mild anti-HSV-1 activity, and 7 showed significant antilarval activity towards Balanus amphitrite larvae.
Keywords: Echinogorgia pseudossapo; gorgonian; zoanthoxanthin alkaloid; sesquiterpene Echinogorgia pseudossapo; gorgonian; zoanthoxanthin alkaloid; sesquiterpene
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Gao, C.-H.; Wang, Y.-F.; Li, S.; Qian, P.-Y.; Qi, S.-H. Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo. Mar. Drugs 2011, 9, 2479-2487.

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