Mar. Drugs 2010, 8(7), 2014-2020; doi:10.3390/md8072014
Article

Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)

Received: 12 May 2010; in revised form: 8 June 2010 / Accepted: 28 June 2010 / Published: 29 June 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A new bioactive sterol glycoside, 3β-O-(3',4'-di-O-acetyl-β-D-arabinopyranosyl)-25ξ-cholestane-3β,5α,6β,26-tetrol-26-acetate) (carijoside A, 1), was isolated from an octocoral identified as Carijoa sp. The structure of glycoside 1 was established by spectroscopic methods and by comparison with spectral data for the other known glycosides. Carijoside A (1) displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils and this compound exhibited moderate cytotoxicity toward DLD-1, P388D1, HL-60, and CCRF-CEM tumor cells.
Keywords: Carijoa; carijoside; glycoside; superoxide anion; elastase; cytotoxicity
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MDPI and ACS Style

Liu, C.-Y.; Hwang, T.-L.; Lin, M.-R.; Chen, Y.-H.; Chang, Y.-C.; Fang, L.-S.; Wang, W.-H.; Wu, Y.-C.; Sung, P.-J. Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae). Mar. Drugs 2010, 8, 2014-2020.

AMA Style

Liu C-Y, Hwang T-L, Lin M-R, Chen Y-H, Chang Y-C, Fang L-S, Wang W-H, Wu Y-C, Sung P-J. Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae). Marine Drugs. 2010; 8(7):2014-2020.

Chicago/Turabian Style

Liu, Chih-Yang; Hwang, Tsong-Long; Lin, Mei-Ru; Chen, Yung-Husan; Chang, Yu-Chia; Fang, Lee-Shing; Wang, Wei-Hsien; Wu, Yang-Chang; Sung, Ping-Jyun. 2010. "Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)." Mar. Drugs 8, no. 7: 2014-2020.

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