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Correction: Banack, S.A. et al. Production of the Neurotoxin BMAA by a Marine Cyanobacterium. Mar. Drugs 2007, 5, 180–196
Mar. Drugs 2010, 8(7), 2014-2020; doi:10.3390/md8072014
Article

Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)

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1 Department of Life Science and Graduate Institute of Biotechnology, Graduate Institute of Marine Biotechnology, National Dong Hwa University, Checheng, Pingtung 944, Taiwan 2 National Museum of Marine Biology and Aquarium, Checheng, Pingtung 944, Taiwan 3 Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan 4 Department of Sport, Health, and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan 5 Department of Marine Biotechnology and Resources, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan 6 Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
* Authors to whom correspondence should be addressed.
Received: 12 May 2010 / Revised: 8 June 2010 / Accepted: 28 June 2010 / Published: 29 June 2010
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Abstract

A new bioactive sterol glycoside, 3β-O-(3',4'-di-O-acetyl-β-D-arabinopyranosyl)-25ξ-cholestane-3β,5α,6β,26-tetrol-26-acetate) (carijoside A, 1), was isolated from an octocoral identified as Carijoa sp. The structure of glycoside 1 was established by spectroscopic methods and by comparison with spectral data for the other known glycosides. Carijoside A (1) displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils and this compound exhibited moderate cytotoxicity toward DLD-1, P388D1, HL-60, and CCRF-CEM tumor cells.
Keywords: Carijoa; carijoside; glycoside; superoxide anion; elastase; cytotoxicity Carijoa; carijoside; glycoside; superoxide anion; elastase; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Liu, C.-Y.; Hwang, T.-L.; Lin, M.-R.; Chen, Y.-H.; Chang, Y.-C.; Fang, L.-S.; Wang, W.-H.; Wu, Y.-C.; Sung, P.-J. Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae). Mar. Drugs 2010, 8, 2014-2020.

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