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Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea
School of Pharmacy, Guangdong Medical College, Dongguan, 523808, China
Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China
School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou, 510275, China
* Authors to whom correspondence should be addressed.
Received: 4 March 2010; in revised form: 17 March 2010 / Accepted: 26 March 2010 / Published: 29 March 2010
Abstract: Three new phenolic bisabolane-type sesquiterpenoids: (+)-methyl sydowate (1), 7-deoxy-7,14-didehydrosydonic acid (2), and 7-deoxy-7,8-didehydrosydonic acid (3), together with two known fungal metabolites were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated in turn from a gorgonian Dichotella gemmacea collected from the South China Sea. Their structures were elucidated by combined spectroscopic methods, and the structure of 1 was further confirmed by single-crystal X-ray data.
Keywords: phenolic bisabolane-type sesquiterpenoid; Aspergillus sp.; gorgonian Dichotella gemmacea
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Cite This Article
MDPI and ACS Style
Wei, M.-Y.; Wang, C.-Y.; Liu, Q.-A.; Shao, C.-L.; She, Z.-G.; Lin, Y.-C. Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea. Mar. Drugs 2010, 8, 941-949.
Wei M-Y, Wang C-Y, Liu Q-A, Shao C-L, She Z-G, Lin Y-C. Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea. Marine Drugs. 2010; 8(4):941-949.
Wei, Mei-Yan; Wang, Chang-Yun; Liu, Qing-Ai; Shao, Chang-Lun; She, Zhi-Gang; Lin, Yong-Cheng. 2010. "Five Sesquiterpenoids from a Marine-Derived Fungus Aspergillus sp. Isolated from a Gorgonian Dichotella gemmacea." Mar. Drugs 8, no. 4: 941-949.