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Mar. Drugs 2010, 8(12), 2936-2945; doi:10.3390/md8122936
Article

Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp.

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Received: 29 October 2010; in revised form: 25 November 2010 / Accepted: 1 December 2010 / Published: 6 December 2010
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Abstract: Two new eunicellin-type diterpenoids, cladielloides A (1) and B (2), which were found to possess a 2-hydroxybutyroxy group in their structures, were isolated from an Indonesian octocoral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods. Cladielloide B (2) exhibited moderate cytotoxicity toward CCRF-CEM tumor cells and this compound displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils.
Keywords: cladielloide; eunicellin; octocoral; cytotoxicity; superoxide anion; elastase cladielloide; eunicellin; octocoral; cytotoxicity; superoxide anion; elastase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Chen, Y.-H.; Tai, C.-Y.; Hwang, T.-L.; Weng, C.-F.; Li, J.-J.; Fang, L.-S.; Wang, W.-H.; Wu, Y.-C.; Sung, P.-J. Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp.. Mar. Drugs 2010, 8, 2936-2945.

AMA Style

Chen Y-H, Tai C-Y, Hwang T-L, Weng C-F, Li J-J, Fang L-S, Wang W-H, Wu Y-C, Sung P-J. Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp.. Marine Drugs. 2010; 8(12):2936-2945.

Chicago/Turabian Style

Chen, Yung-Husan; Tai, Chia-Ying; Hwang, Tsong-Long; Weng, Ching-Feng; Li, Jan-Jung; Fang, Lee-Shing; Wang, Wei-Hsien; Wu, Yang-Chang; Sung, Ping-Jyun. 2010. "Cladielloides A and B: New Eunicellin-Type Diterpenoids from an Indonesian Octocoral Cladiella sp.." Mar. Drugs 8, no. 12: 2936-2945.



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