Next Article in Journal
Recent N-Atom Containing Compounds from Indo-Pacific Invertebrates
Previous Article in Journal
Marine Bacterial Sialyltransferases
Mar. Drugs 2010, 8(11), 2795-2809; doi:10.3390/md8112795
Article

Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei)

1
, 1
, 2,†
, 1
, 2
, 3
, 1
, 1
, 2
 and 1,†,*
Received: 26 September 2010; in revised form: 14 October 2010 / Accepted: 2 November 2010 / Published: 8 November 2010
View Full-Text   |   Download PDF [311 KB, uploaded 8 November 2010]   |   Browse Figures
Abstract: An organic extract from fresh shrimp (Litopenaeus vannamei) was studied for antimutagenic and antiproliferative properties using Salmonella typhimurium tester strains TA98 and TA100 with metabolic activation (S9) and a cancer cell line (B-cell lymphoma), respectively. Shrimp extract was sequentially fractionated by thin layer chromatography (TLC) and each fraction was tested for antimutagenic and antiproliferative activities. Crude organic extracts obtained from shrimp reduced the number of revertants caused by aflatoxina B1, showing a dose-response type of relationship. Sequential TLC fractionation of the active extracts produced several antimutagenic and/or antiproliferative fractions. These results suggested that the lipid fraction of the tested species contained compounds with chemoprotective properties that reduce the mutagenicity of AFB1 and proliferation of a cancer cell line.
Keywords: antimutagenicity; antiproliferation; cultured shrimp antimutagenicity; antiproliferation; cultured shrimp
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Wilson-Sanchez, G.; Moreno-Félix, C.; Velazquez, C.; Plascencia-Jatomea, M.; Acosta, A.; Machi-Lara, L.; Aldana-Madrid, M.-L.; Ezquerra-Brauer, J.-M.; Robles-Zepeda, R.; Burgos-Hernandez, A. Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei). Mar. Drugs 2010, 8, 2795-2809.

AMA Style

Wilson-Sanchez G, Moreno-Félix C, Velazquez C, Plascencia-Jatomea M, Acosta A, Machi-Lara L, Aldana-Madrid M-L, Ezquerra-Brauer J-M, Robles-Zepeda R, Burgos-Hernandez A. Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei). Marine Drugs. 2010; 8(11):2795-2809.

Chicago/Turabian Style

Wilson-Sanchez, Griselda; Moreno-Félix, Carolina; Velazquez, Carlos; Plascencia-Jatomea, Maribel; Acosta, Anita; Machi-Lara, Lorena; Aldana-Madrid, María-Lourdes; Ezquerra-Brauer, Josafat-Marina; Robles-Zepeda, Ramón; Burgos-Hernandez, Armando. 2010. "Antimutagenicity and Antiproliferative Studies of Lipidic Extracts from White Shrimp (Litopenaeus vannamei)." Mar. Drugs 8, no. 11: 2795-2809.


Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert