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• Genovese, G
• Tedone, L
• Hamann, MT.
• Morabito, M
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• Tedone, L
• Hamann, MT.
• Morabito, M
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• Genovese, G
• Tedone, L
• Hamann, MT.
• Morabito, M

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Mar. Drugs 2009, 7(3), 361-366; doi:10.3390/md7030361

Article

The Mediterranean Red Alga Asparagopsis: A Source of Compounds against Leishmania

Giuseppa Genovese ^1,* , Laura Tedone ^1,2, Mark T. Hamann ² and Marina Morabito ¹

¹ Department of Life Sciences \"M. Malpighi\"-Botany, University of Messina, Salita Sperone, 31, 98166 Messina, Italy ² School of Pharmacy, University of Mississippi, 407 Faser Hall, University MS 38677, USA

* Author to whom correspondence should be addressed.

Received: 23 July 2009; in revised form: 7 August 2009 / Accepted: 10 August 2009 / Published: 11 August 2009

Download PDF Full-Text [115 KB, uploaded 10 August 2009 23:08 CEST]

Abstract: Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds. Extracts from both species revealed remarkable antiprotozoal activity against Leishmania, revealing such algae as a great source of natural antiprotozoal products.

Keywords: antiprotozoal products; Asparagopsis armata; Asparagopsis taxiformis; halogenated metabolites; Leishmania; marine natural products

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