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The Occurrence of Bioactive Micromonosporae in Aquatic Habitats of the Sunshine Coast in Australia
Faculty of Science, Health and Education, University of the Sunshine Coast, Maroochydore DC, Qld 4558, Australia
* Author to whom correspondence should be addressed.
Received: 31 March 2008; in revised form: 19 May 2008 / Accepted: 23 May 2008 / Published: 5 June 2008
Abstract: Screening strategies based on the ecological knowledge of antibiotic producing microorganisms and their roles in the natural environment are being increasingly employed in the search for novel antibiotic agents. Micromonosporae are common inhabitants of aquatic habitats and have proved to be a continuing source of novel bioactive compounds including antibacterial and antitumor agents. The ecological distribution and frequency of bioactive micromonosporae in Sunshine Coast region aquatic habitats were studied through a range of selective isolation procedures designed to negatively select against the isolation of unwanted microbial taxa commonly associated with marine environments. It was revealed that bioactive compound producing species of micromonosporae were present in the aquatic habitats of the Sunshine Coast region in Australia.
Keywords: Actinomycetes; Micromonosporae; Bioactive compounds; Gentamicin; Aquatic habitats
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Eccleston, G.P.; Brooks, P.R.; Kurtböke, D.I. The Occurrence of Bioactive Micromonosporae in Aquatic Habitats of the Sunshine Coast in Australia. Mar. Drugs 2008, 6, 243-261.
Eccleston GP, Brooks PR, Kurtböke DI. The Occurrence of Bioactive Micromonosporae in Aquatic Habitats of the Sunshine Coast in Australia. Marine Drugs. 2008; 6(2):243-261.
Eccleston, Glen P.; Brooks, Peter R.; Kurtböke, D. I. 2008. "The Occurrence of Bioactive Micromonosporae in Aquatic Habitats of the Sunshine Coast in Australia." Mar. Drugs 6, no. 2: 243-261.