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Mar. Drugs 2006, 4(3), 228-254; doi:10.3390/md403228
Review

The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors

1,*  and 2
Received: 25 January 2006; Accepted: 31 January 2006 / Published: 6 April 2006
(This article belongs to the Special Issue Marine Drugs and Ion Channels)
Abstract: This chapter covers the chemistry and nicotinic pharmacology of naturally occurring homotropane alkaloids, with an emphasis of anatoxin-a. In addition to anatoxin-a, homoanatoxin and pinnamine, as well as the major classes of synthetic derivatives of anatoxin-a including UB-165, are discussed.
Keywords: anatoxin-a; homoanatoxin; UB165; pinnamine; homotropane; nicotinic acetylcholine receptor; pharmacophore anatoxin-a; homoanatoxin; UB165; pinnamine; homotropane; nicotinic acetylcholine receptor; pharmacophore
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wonnacott, S.; Gallagher, T. The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors. Mar. Drugs 2006, 4, 228-254.

AMA Style

Wonnacott S, Gallagher T. The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors. Marine Drugs. 2006; 4(3):228-254.

Chicago/Turabian Style

Wonnacott, Susan; Gallagher, Timothy. 2006. "The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors." Mar. Drugs 4, no. 3: 228-254.



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