Next Article in Journal / Special Issue
The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties
Previous Article in Journal / Special Issue
New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels
Article Menu

Export Article

Open AccessReview
Mar. Drugs 2006, 4(3), 228-254; doi:10.3390/md403228

The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors

1
Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK
2
School of Chemistry, University of Bristol, Bristol BS8 1TS, UK
*
Author to whom correspondence should be addressed.
Received: 25 January 2006 / Accepted: 31 January 2006 / Published: 6 April 2006
(This article belongs to the Special Issue Marine Drugs and Ion Channels)
View Full-Text   |   Download PDF [186 KB, uploaded 24 February 2015]   |  

Abstract

This chapter covers the chemistry and nicotinic pharmacology of naturally occurring homotropane alkaloids, with an emphasis of anatoxin-a. In addition to anatoxin-a, homoanatoxin and pinnamine, as well as the major classes of synthetic derivatives of anatoxin-a including UB-165, are discussed.
Keywords: anatoxin-a; homoanatoxin; UB165; pinnamine; homotropane; nicotinic acetylcholine receptor; pharmacophore anatoxin-a; homoanatoxin; UB165; pinnamine; homotropane; nicotinic acetylcholine receptor; pharmacophore
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Wonnacott, S.; Gallagher, T. The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors. Mar. Drugs 2006, 4, 228-254.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top