Mar. Drugs 2005, 3(1), 15-21; doi:10.3390/md301015
Article

Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco

Saida Rifai 1 , Aziz Fassouane 1 , Paulo M. Pinho 2 , Anake Kijjoa 2,* email, Nair Nazareth 3 , Maria São José Nascimento 3  and Werner Herz 4
1 Faculté des Sciences, Université Chouäib Doukkali, El Jadida, Morocco 2 ICBAS- Instituto de Ciências Biomédicas de Abel Salazar and CIIMAR, Universidade do Porto, 4099-003 Porto, Portugal 3 Centro de Estudos de Química Orgânica, Fitoquímica e Farmacologia da Universidade do Porto, Faculdade de Farmácia, Rua Anibal Cunha 164, 4050-047, Porto, Portugal 4 Department of Chemistry and Biochemistry, Florida State University,Tallahassee, FL 32306-4390, USA
* Author to whom correspondence should be addressed.
Received: 16 February 2005 / Accepted: 15 March 2005 / Published: 15 March 2005
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Abstract: Fasciculatin, a furanosesterterpene isolated from the marine sponge Ircinia variabilis from the Atlantic Coast of Morocco, has been evaluated for its influence on a mitogen-induced proliferation of human lymphocytes and growth of human tumor cell lines.
Keywords: Porifera; Ircinia variabilis; cytotoxicity; human tumor cell lines; inhibition of lymphocyte proliferation

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MDPI and ACS Style

Rifai, S.; Fassouane, A.; Pinho, P.M.; Kijjoa, A.; Nazareth, N.; Nascimento, M.S.J.; Herz, W. Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco. Mar. Drugs 2005, 3, 15-21.

AMA Style

Rifai S, Fassouane A, Pinho PM, Kijjoa A, Nazareth N, Nascimento MSJ, Herz W. Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco. Marine Drugs. 2005; 3(1):15-21.

Chicago/Turabian Style

Rifai, Saida; Fassouane, Aziz; Pinho, Paulo M.; Kijjoa, Anake; Nazareth, Nair; Nascimento, Maria S.J.; Herz, Werner. 2005. "Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco." Mar. Drugs 3, no. 1: 15-21.

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