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Mar. Drugs 2005, 3(1), 15-21; doi:10.3390/md301015
Article

Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco

1, 1, 2, 2,* , 3, 3 and 4
1 Faculté des Sciences, Université Chouäib Doukkali, El Jadida, Morocco 2 ICBAS- Instituto de Ciências Biomédicas de Abel Salazar and CIIMAR, Universidade do Porto, 4099-003 Porto, Portugal 3 Centro de Estudos de Química Orgânica, Fitoquímica e Farmacologia da Universidade do Porto, Faculdade de Farmácia, Rua Anibal Cunha 164, 4050-047, Porto, Portugal 4 Department of Chemistry and Biochemistry, Florida State University,Tallahassee, FL 32306-4390, USA
* Author to whom correspondence should be addressed.
Received: 16 February 2005 / Accepted: 15 March 2005 / Published: 15 March 2005
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Abstract

Fasciculatin, a furanosesterterpene isolated from the marine sponge Ircinia variabilis from the Atlantic Coast of Morocco, has been evaluated for its influence on a mitogen-induced proliferation of human lymphocytes and growth of human tumor cell lines.
Keywords: Porifera; Ircinia variabilis; cytotoxicity; human tumor cell lines; inhibition of lymphocyte proliferation Porifera; Ircinia variabilis; cytotoxicity; human tumor cell lines; inhibition of lymphocyte proliferation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Rifai, S.; Fassouane, A.; Pinho, P.M.; Kijjoa, A.; Nazareth, N.; Nascimento, M.S.J.; Herz, W. Cytotoxicity and Inhibition of Lymphocyte Proliferation of Fasciculatin, a Linear Furanosesterterpene Isolated from Ircinia variabilis Collected from the Atlantic Coast of Morocco. Mar. Drugs 2005, 3, 15-21.

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