Mar. Drugs 2005, 3(2), 22-28; doi:10.3390/md302022
Article

New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai

Sachiko Tsukamoto* email, Yuko Yamashita and Tomihisa Ohta
Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan
* Author to whom correspondence should be addressed.
Received: 31 January 2005 / Accepted: 15 April 2005 / Published: 16 April 2005
PDF Full-text Download PDF Full-Text [68 KB, uploaded 28 August 2008 16:06 CEST]
Abstract: The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolaurinterol acetate by spectroscopic analysis. Although the acetates were derived from laurinterol and debromolaurinterol before, this is the first isolation of the acetates from natural sources.
Keywords: cytotoxicity; antibacterial activity; laurinterol acetate; debromolaurinterol acetate; sea hare; Aplysia kurodai

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Tsukamoto, S.; Yamashita, Y.; Ohta, T. New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai. Mar. Drugs 2005, 3, 22-28.

AMA Style

Tsukamoto S, Yamashita Y, Ohta T. New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai. Marine Drugs. 2005; 3(2):22-28.

Chicago/Turabian Style

Tsukamoto, Sachiko; Yamashita, Yuko; Ohta, Tomihisa. 2005. "New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai." Mar. Drugs 3, no. 2: 22-28.

Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert