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Mar. Drugs 2004, 2(3), 101-107; doi:10.3390/md203101
Article

Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge

1, 1, 1, 2 and 3,*
Received: 7 May 2004; Accepted: 1 August 2004 / Published: 25 August 2004
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Abstract: The known chromodorolides A (1) and B (2), and a new derivative chromodorolide C (3) have been isolated from an Australian sponge and characterized by 1D and 2D NMR experiments. The chromodorolides exhibited significant cytotoxicity against the P388 mouse leukaemia cell line, and also showed activity against the freeliving larval stages of the parasitic nematodes Haemonchus contortus and Trichostrongylus colubriformis.
Keywords: Marine sponges; secondary metabolites; diterpenes; chromodoranes; anthelmintic activity Marine sponges; secondary metabolites; diterpenes; chromodoranes; anthelmintic activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Rungprom, W.; Chavasiri, W.; Kokpol, U.; Kotze, A.; Garson, M.J. Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge. Mar. Drugs 2004, 2, 101-107.

AMA Style

Rungprom W, Chavasiri W, Kokpol U, Kotze A, Garson MJ. Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge. Marine Drugs. 2004; 2(3):101-107.

Chicago/Turabian Style

Rungprom, Wimolpun; Chavasiri, Warinthorn; Kokpol, Udom; Kotze, Andrew; Garson, Mary J. 2004. "Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge." Mar. Drugs 2, no. 3: 101-107.


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