Next Article in Journal
Healing and Preventive Effects of Calcium Alginate on Carbon Tetrachloride Induced Liver Injury in Rats
Previous Article in Journal
New Alkaloids from the Mediterranean Sponge Hamigera hamigera
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2004, 2(3), 101-107; doi:10.3390/md203101

Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge

Natural Products Research Unit, Department of Chemistry, Chulalongkorn University, Bangkok 10330, Thailand
CSIRO Livestock Industries, Queensland Bioscience Precinct, Brisbane 4067, Australia
Department of Chemistry, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane 4072, Australia
Author to whom correspondence should be addressed.
Received: 7 May 2004 / Accepted: 1 August 2004 / Published: 25 August 2004
View Full-Text   |   Download PDF [46 KB, uploaded 24 February 2015]   |  


The known chromodorolides A (1) and B (2), and a new derivative chromodorolide C (3) have been isolated from an Australian sponge and characterized by 1D and 2D NMR experiments. The chromodorolides exhibited significant cytotoxicity against the P388 mouse leukaemia cell line, and also showed activity against the freeliving larval stages of the parasitic nematodes Haemonchus contortus and Trichostrongylus colubriformis.
Keywords: Marine sponges; secondary metabolites; diterpenes; chromodoranes; anthelmintic activity Marine sponges; secondary metabolites; diterpenes; chromodoranes; anthelmintic activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Rungprom, W.; Chavasiri, W.; Kokpol, U.; Kotze, A.; Garson, M.J. Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge. Mar. Drugs 2004, 2, 101-107.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top