Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1
AbstractEutypenoids A–C (1–3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A–C (1–3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities. View Full-Text
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Zhang, L.-Q.; Chen, X.-C.; Chen, Z.-Q.; Wang, G.-M.; Zhu, S.-G.; Yang, Y.-F.; Chen, K.-X.; Liu, X.-Y.; Li, Y.-M. Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1. Mar. Drugs 2016, 14, 44.
Zhang L-Q, Chen X-C, Chen Z-Q, Wang G-M, Zhu S-G, Yang Y-F, Chen K-X, Liu X-Y, Li Y-M. Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1. Marine Drugs. 2016; 14(3):44.Chicago/Turabian Style
Zhang, Liu-Qiang; Chen, Xiao-Chong; Chen, Zhao-Qiang; Wang, Gui-Min; Zhu, Shi-Guo; Yang, Yi-Fu; Chen, Kai-Xian; Liu, Xiao-Yu; Li, Yi-Ming. 2016. "Eutypenoids A–C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1." Mar. Drugs 14, no. 3: 44.
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