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Mar. Drugs 2015, 13(11), 6910-6946; doi:10.3390/md13116910

Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge

1
Faculty of Sciences, University of Porto, Rua do Campo Alegre, Porto 4169-007, Portugal
2
Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Rua dos Bragas 289, Porto 4050-123, Portugal
*
Author to whom correspondence should be addressed.
Academic Editor: Michèle Prinsep
Received: 25 June 2015 / Revised: 22 September 2015 / Accepted: 30 October 2015 / Published: 13 November 2015
(This article belongs to the Special Issue Compounds from Cyanobacteria)
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Abstract

Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential. View Full-Text
Keywords: cyanobacteria; cyanobactins; genetic clusters; chemical structures; bioactivities; ecological roles; biotechnological potential cyanobacteria; cyanobactins; genetic clusters; chemical structures; bioactivities; ecological roles; biotechnological potential
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Martins, J.; Vasconcelos, V. Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge. Mar. Drugs 2015, 13, 6910-6946.

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