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Mar. Drugs 2014, 12(6), 3608-3633; doi:10.3390/md12063608
Review

Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

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Received: 1 April 2014; in revised form: 3 June 2014 / Accepted: 4 June 2014 / Published: 12 June 2014
(This article belongs to the Special Issue Bioactive Compounds from Marine Invertebrates)
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Abstract: Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.
Keywords: ascidian secondary metabolites; structure elucidation; bioactivity; 13C-NMR spectral data; quinones; hydroquinones ascidian secondary metabolites; structure elucidation; bioactivity; 13C-NMR spectral data; quinones; hydroquinones
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bertanha, C.S.; Januário, A.H.; Alvarenga, T.A.; Pimenta, L.P.; Silva, M.L.A.; Cunha, W.R.; Pauletti, P.M. Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium. Mar. Drugs 2014, 12, 3608-3633.

AMA Style

Bertanha CS, Januário AH, Alvarenga TA, Pimenta LP, Silva MLA, Cunha WR, Pauletti PM. Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium. Marine Drugs. 2014; 12(6):3608-3633.

Chicago/Turabian Style

Bertanha, Camila S.; Januário, Ana H.; Alvarenga, Tavane A.; Pimenta, Letícia P.; Silva, Márcio L.A.; Cunha, Wilson R.; Pauletti, Patrícia M. 2014. "Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium." Mar. Drugs 12, no. 6: 3608-3633.


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