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Mar. Drugs 2014, 12(3), 1271-1280; doi:10.3390/md12031271
Communication

Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B

1,* , 1
 and 2
Received: 6 January 2014; in revised form: 8 February 2014 / Accepted: 18 February 2014 / Published: 6 March 2014
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Abstract: Three new spirobisnaphthalenes (13) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (48). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 35 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells.
Keywords: endophytic fungus; Rhytidhysteron sp.; spirobisnaphthalene; cytotoxicity endophytic fungus; Rhytidhysteron sp.; spirobisnaphthalene; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Pudhom, K.; Teerawatananond, T.; Chookpaiboon, S. Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B. Mar. Drugs 2014, 12, 1271-1280.

AMA Style

Pudhom K, Teerawatananond T, Chookpaiboon S. Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B. Marine Drugs. 2014; 12(3):1271-1280.

Chicago/Turabian Style

Pudhom, Khanitha; Teerawatananond, Thapong; Chookpaiboon, Supichar. 2014. "Spirobisnaphthalenes from the Mangrove-Derived Fungus Rhytidhysteron sp. AS21B." Mar. Drugs 12, no. 3: 1271-1280.


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