Marine Natural Products with P-Glycoprotein Inhibitor Properties
AbstractP-glycoprotein (P-gp) is a protein belonging to the ATP-binding cassette (ABC) transporters superfamily that has clinical relevance due to its role in drug metabolism and multi-drug resistance (MDR) in several human pathogens and diseases. P-gp is a major cause of drug resistance in cancer, parasitic diseases, epilepsy and other disorders. This review article aims to summarize the research findings on the marine natural products with P-glycoprotein inhibitor properties. Natural compounds that modulate P-gp offer great possibilities for semi-synthetic modification to create new drugs and are valuable research tools to understand the function of complex ABC transporters. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Lopez, D.; Martinez-Luis, S. Marine Natural Products with P-Glycoprotein Inhibitor Properties. Mar. Drugs 2014, 12, 525-546.
Lopez D, Martinez-Luis S. Marine Natural Products with P-Glycoprotein Inhibitor Properties. Marine Drugs. 2014; 12(1):525-546.Chicago/Turabian Style
Lopez, Dioxelis; Martinez-Luis, Sergio. 2014. "Marine Natural Products with P-Glycoprotein Inhibitor Properties." Mar. Drugs 12, no. 1: 525-546.