Secosteroids and Norcembranoids from the Soft Coral Sinularia nanolobata
AbstractTwo new 9,11-secosteroids, 22α-acetoxy-24-methylene-3β,6α,11-trihydroxy-9, 11-seco-cholest-7-en-9-one (1) and 11-acetoxy-24-methylene-1β,3β,6α-trihydroxy-9, 11-seco-cholest-7-en-9-one (2), as well as two known norcembranoids, 5-epi-sinuleptolide (3) and sinuleptolide (4), were isolated from the soft coral Sinularia nanolobata. The structures of these metabolites were elucidated on the basis of extensive spectroscopic analysis. The anti-HCMV (human cytomegalovirus) activity of 1–4 and its cytotoxicity against selected cell lines were evaluated.
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Tseng, Y.-J.; Wang, S.-K.; Duh, C.-Y. Secosteroids and Norcembranoids from the Soft Coral Sinularia nanolobata. Mar. Drugs 2013, 11, 3288-3296.
Tseng Y-J, Wang S-K, Duh C-Y. Secosteroids and Norcembranoids from the Soft Coral Sinularia nanolobata. Marine Drugs. 2013; 11(9):3288-3296.Chicago/Turabian Style
Tseng, Yen-Ju; Wang, Shang-Kwei; Duh, Chang-Yih. 2013. "Secosteroids and Norcembranoids from the Soft Coral Sinularia nanolobata." Mar. Drugs 11, no. 9: 3288-3296.