Mar. Drugs 2013, 11(2), 455-465; doi:10.3390/md11020455
Article

New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.

1,†email, 1,†email, 2email, 1email, 1email, 1email, 1email, 2email, 1,* email and 1,* email
Received: 6 November 2012; in revised form: 15 January 2013 / Accepted: 29 January 2013 / Published: 6 February 2013
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Six new casbane diterpenoids, named as sinularcasbanes A–F (1–6), along with six known analogues 7–12, were isolated from a South China Sea soft coral, Sinularia sp. The structures of the new compounds were elucidated by extensive spectroscopic analysis and by comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against selected cancer cell lines and the inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages.
Keywords: soft coral; Sinularia; casbane diterpenoids; cytotoxicity; NO inhibition
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MDPI and ACS Style

Yin, J.; Zhao, M.; Ma, M.; Xu, Y.; Xiang, Z.; Cai, Y.; Dong, J.; Lei, X.; Huang, K.; Yan, P. New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.. Mar. Drugs 2013, 11, 455-465.

AMA Style

Yin J, Zhao M, Ma M, Xu Y, Xiang Z, Cai Y, Dong J, Lei X, Huang K, Yan P. New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.. Marine Drugs. 2013; 11(2):455-465.

Chicago/Turabian Style

Yin, Jian; Zhao, Min; Ma, Minshan; Xu, Yuping; Xiang, Zheng; Cai, Yuepiao; Dong, Jianyong; Lei, Xinxiang; Huang, Kexin; Yan, Pengcheng. 2013. "New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.." Mar. Drugs 11, no. 2: 455-465.

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