Next Article in Journal
Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA
Previous Article in Journal
Core Oligosaccharide of Plesiomonas shigelloides PCM 2231 (Serotype O17) Lipopolysaccharide — Structural and Serological Analysis
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2013, 11(2), 455-465; doi:10.3390/md11020455

New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.

School of Pharmacy, Wenzhou Medical College, Wenzhou 325035, China
Analytical and Testing Center, Wenzhou University, Wenzhou 325035, China
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Received: 6 November 2012 / Revised: 15 January 2013 / Accepted: 29 January 2013 / Published: 6 February 2013
View Full-Text   |   Download PDF [696 KB, uploaded 24 February 2015]   |  


Six new casbane diterpenoids, named as sinularcasbanes A–F (1–6), along with six known analogues 7–12, were isolated from a South China Sea soft coral, Sinularia sp. The structures of the new compounds were elucidated by extensive spectroscopic analysis and by comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against selected cancer cell lines and the inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages. View Full-Text
Keywords: soft coral; Sinularia; casbane diterpenoids; cytotoxicity; NO inhibition soft coral; Sinularia; casbane diterpenoids; cytotoxicity; NO inhibition

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary materials

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Yin, J.; Zhao, M.; Ma, M.; Xu, Y.; Xiang, Z.; Cai, Y.; Dong, J.; Lei, X.; Huang, K.; Yan, P. New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.. Mar. Drugs 2013, 11, 455-465.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top