Cyclic Bis-1,3-dialkylpyridiniums from the Sponge Haliclona sp.
AbstractEight novel cyclic bis-1,3-dialkylpyridiniums, as well as two known compounds from the cyclostellettamine class, were isolated from the sponge Haliclona sp. from Korea. Structures of these novel compounds were determined using combined NMR and FAB-MS/MS analyses. Several of these compounds exhibited moderate cytotoxic and antibacterial activities against A549 cell-line and Gram-positive strains, respectively. The structure-activity relationships of cyclostellettamines are discussed based on their bioactivities.
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Lee, Y.; Jang, K.H.; Jeon, J.-E.; Yang, W.-Y.; Sim, C.J.; Oh, K.-B.; Shin, J. Cyclic Bis-1,3-dialkylpyridiniums from the Sponge Haliclona sp.. Mar. Drugs 2012, 10, 2126-2137.
Lee Y, Jang KH, Jeon J-E, Yang W-Y, Sim CJ, Oh K-B, Shin J. Cyclic Bis-1,3-dialkylpyridiniums from the Sponge Haliclona sp.. Marine Drugs. 2012; 10(9):2126-2137.Chicago/Turabian Style
Lee, Yoonyeong; Jang, Kyoung Hwa; Jeon, Ju-eun; Yang, Woo-Young; Sim, Chung J.; Oh, Ki-Bong; Shin, Jongheon. 2012. "Cyclic Bis-1,3-dialkylpyridiniums from the Sponge Haliclona sp.." Mar. Drugs 10, no. 9: 2126-2137.