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Mar. Drugs 2012, 10(8), 1662-1670; doi:10.3390/md10081662

Briareolate Esters from the Gorgonian Briareum asbestinum

1 Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA 2 Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA 3 Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, GA 30602, USA
* Author to whom correspondence should be addressed.
Received: 5 June 2012 / Revised: 25 July 2012 / Accepted: 30 July 2012 / Published: 10 August 2012
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Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).
Keywords: Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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Meginley, R.J.; Gupta, P.; Schulz, T.C.; McLean, A.B.; Robins, A.J.; West, L.M. Briareolate Esters from the Gorgonian Briareum asbestinum. Mar. Drugs 2012, 10, 1662-1670.

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