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Briareolate Esters from the Gorgonian Briareum asbestinum
Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA
Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA
Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, GA 30602, USA
* Author to whom correspondence should be addressed.
Received: 5 June 2012; in revised form: 25 July 2012 / Accepted: 30 July 2012 / Published: 10 August 2012
Abstract: Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).
Keywords: Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell
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Meginley, R.J.; Gupta, P.; Schulz, T.C.; McLean, A.B.; Robins, A.J.; West, L.M. Briareolate Esters from the Gorgonian Briareum asbestinum. Mar. Drugs 2012, 10, 1662-1670.
Meginley RJ, Gupta P, Schulz TC, McLean AB, Robins AJ, West LM. Briareolate Esters from the Gorgonian Briareum asbestinum. Marine Drugs. 2012; 10(8):1662-1670.
Meginley, Rian J.; Gupta, Prasoon; Schulz, Thomas C.; McLean, Amanda B.; Robins, Allan J.; West, Lyndon M. 2012. "Briareolate Esters from the Gorgonian Briareum asbestinum." Mar. Drugs 10, no. 8: 1662-1670.