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Mar. Drugs 2012, 10(8), 1662-1670; doi:10.3390/md10081662
Article

Briareolate Esters from the Gorgonian Briareum asbestinum

1
,
1
,
2
,
3
,
2
 and
1,*
1 Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA 2 Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA 3 Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, GA 30602, USA
* Author to whom correspondence should be addressed.
Received: 5 June 2012 / Revised: 25 July 2012 / Accepted: 30 July 2012 / Published: 10 August 2012
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Abstract

Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).
Keywords: Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Meginley, R.J.; Gupta, P.; Schulz, T.C.; McLean, A.B.; Robins, A.J.; West, L.M. Briareolate Esters from the Gorgonian Briareum asbestinum. Mar. Drugs 2012, 10, 1662-1670.

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