Mar. Drugs 2012, 10(2), 306-318; doi:10.3390/md10020306
Article

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

Shang-Kwei Wang 1 email and Chang-Yih Duh 2,3,* email
1 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 2 Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan 3 Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 23 December 2011; in revised form: 20 January 2012 / Accepted: 20 January 2012 / Published: 31 January 2012
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Abstract: Six new cembranolides, michaolides L–Q (1–6), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 1–7 and their cytotoxicity against selected cell lines were evaluated.
Keywords: Lobophytum michaelae; cembranolides; cytotoxicity

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Cite This Article

MDPI and ACS Style

Wang, S.-K.; Duh, C.-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Mar. Drugs 2012, 10, 306-318.

AMA Style

Wang S-K, Duh C-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Marine Drugs. 2012; 10(2):306-318.

Chicago/Turabian Style

Wang, Shang-Kwei; Duh, Chang-Yih. 2012. "New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae." Mar. Drugs 10, no. 2: 306-318.

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