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Mar. Drugs 2012, 10(2), 306-318; doi:10.3390/md10020306

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

1 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 2 Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan 3 Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 23 December 2011 / Revised: 20 January 2012 / Accepted: 20 January 2012 / Published: 31 January 2012
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Six new cembranolides, michaolides L–Q (16), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 17 and their cytotoxicity against selected cell lines were evaluated.
Keywords: Lobophytum michaelae; cembranolides; cytotoxicity Lobophytum michaelae; cembranolides; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, S.-K.; Duh, C.-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Mar. Drugs 2012, 10, 306-318.

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