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Mar. Drugs 2012, 10(2), 306-318; doi:10.3390/md10020306
Article

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

1
 and
2,3,*
1 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 2 Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan 3 Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 23 December 2011 / Revised: 20 January 2012 / Accepted: 20 January 2012 / Published: 31 January 2012
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Abstract

Six new cembranolides, michaolides L–Q (16), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 17 and their cytotoxicity against selected cell lines were evaluated.
Keywords: Lobophytum michaelae; cembranolides; cytotoxicity Lobophytum michaelae; cembranolides; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Wang, S.-K.; Duh, C.-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Mar. Drugs 2012, 10, 306-318.

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