Next Article in Journal
Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis
Previous Article in Journal
Tetrodotoxin (TTX) as a Therapeutic Agent for Pain
Mar. Drugs 2012, 10(2), 306-318; doi:10.3390/md10020306

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

1 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 2 Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan 3 Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 23 December 2011 / Revised: 20 January 2012 / Accepted: 20 January 2012 / Published: 31 January 2012
View Full-Text   |   Download PDF [874 KB, 24 February 2015; original version 24 February 2015]   |   Browse Figures


Six new cembranolides, michaolides L–Q (16), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 17 and their cytotoxicity against selected cell lines were evaluated.
Keywords: Lobophytum michaelae; cembranolides; cytotoxicity Lobophytum michaelae; cembranolides; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Wang, S.-K.; Duh, C.-Y. New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae. Mar. Drugs 2012, 10, 306-318.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert