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Mar. Drugs 2012, 10(2), 319-328; doi:10.3390/md10020319
Article

Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis

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Received: 20 December 2011 / Revised: 29 January 2012 / Accepted: 30 January 2012 / Published: 3 February 2012
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Abstract

Four novel amicoumacins, namely lipoamicoumacins A–D (14), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in literature.
Keywords: antibacterial; cytotoxicity; lipoamicoumacin; Bacillus subtilis antibacterial; cytotoxicity; lipoamicoumacin; Bacillus subtilis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Li, Y.; Xu, Y.; Liu, L.; Han, Z.; Lai, P.Y.; Guo, X.; Zhang, X.; Lin, W.; Qian, P.-Y. Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis. Mar. Drugs 2012, 10, 319-328.

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