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The Journal Marine Drugs and the First International Symposium on Marine Drugs (2004)
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Mar. Drugs 2003, 1(1), 18-26; doi:10.3390/md101018

13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea)

Department of Chemistry, School of Pharmacy and Molecular Sciences, James Cook University, Townsville, Qld., 4811, Australia
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Received: 14 February 2003 / Accepted: 16 October 2003 / Published: 15 November 2003
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Abstract

An investigation of the soft coral Asterospicularia laurae collected on the Great Barrier Reef, Australia, afforded the cytotoxic diterpene 13-epi-9-deacetoxyxenicin (1) in addition to the known metabolites 13-epi-9-deacetylxenicin (2) and gorgosterol. 13-Epi-9-deacetoxyxenicin readily underwent an autoxidation reaction in solution to afford a single product, the hydroperoxide 3. Structures, stereochemistry, and NMR assignments were established by high resolution NMR spectroscopy and by comparison with published data for known compounds. View Full-Text
Keywords: Cytotoxic; xenicane diterpene; soft coral; Asterospicularia Cytotoxic; xenicane diterpene; soft coral; Asterospicularia
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Bowden, B.F.; Cusack, B.J.; Dangel, A. 13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea). Mar. Drugs 2003, 1, 18-26.

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