Mar. Drugs 2003, 1(1), 18-26; doi:10.3390/md101018
Article

13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea)

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Received: 14 February 2003; Accepted: 16 October 2003 / Published: 15 November 2003
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: An investigation of the soft coral Asterospicularia laurae collected on the Great Barrier Reef, Australia, afforded the cytotoxic diterpene 13-epi-9-deacetoxyxenicin (1) in addition to the known metabolites 13-epi-9-deacetylxenicin (2) and gorgosterol. 13-Epi-9-deacetoxyxenicin readily underwent an autoxidation reaction in solution to afford a single product, the hydroperoxide 3. Structures, stereochemistry, and NMR assignments were established by high resolution NMR spectroscopy and by comparison with published data for known compounds.
Keywords: Cytotoxic; xenicane diterpene; soft coral; Asterospicularia
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MDPI and ACS Style

Bowden, B.F.; Cusack, B.J.; Dangel, A. 13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea). Mar. Drugs 2003, 1, 18-26.

AMA Style

Bowden BF, Cusack BJ, Dangel A. 13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea). Marine Drugs. 2003; 1(1):18-26.

Chicago/Turabian Style

Bowden, Bruce F.; Cusack, Bernard J.; Dangel, Alissa. 2003. "13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea)." Mar. Drugs 1, no. 1: 18-26.


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