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Mar. Drugs 2003, 1(1), 27-33; doi:10.3390/md101027
Article

Rigidin E, a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species

1, 1, 1, 2 and 1,*
1 Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA 2 Universidade Federal do ParanĂ¡, Departamento de Zoologia, C.P. 19020, 81.531-980, Curitiba, Brazil
* Author to whom correspondence should be addressed.
Received: 18 September 2003 / Accepted: 13 November 2003 / Published: 26 November 2003
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Abstract

A new pyrrolopyrimidine alkaloid, rigidin E (1) and the known metabolites rigidin (2) and 1-methylherbipoline (3) have been isolated from a Papua New Guinea tunicate Eudistoma sp. A combination of spectroscopic data were used to determine the structures of these metabolites.
Keywords: Tunicate; Eudistoma sp.; rigidin E; cytotoxicity; HCT 116; A431 Tunicate; Eudistoma sp.; rigidin E; cytotoxicity; HCT 116; A431
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Davis, R.A.; Christensen, L.V.; Richardson, A.D.; Da Rocha, R.M.; Ireland, C.M. Rigidin E, a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species. Mar. Drugs 2003, 1, 27-33.

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