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Mar. Drugs 2003, 1(1), 27-33; doi:10.3390/md101027
Article

Rigidin E, a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species

1, 1, 1, 2 and 1,*
1 Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA 2 Universidade Federal do ParanĂ¡, Departamento de Zoologia, C.P. 19020, 81.531-980, Curitiba, Brazil
* Author to whom correspondence should be addressed.
Received: 18 September 2003 / Accepted: 13 November 2003 / Published: 26 November 2003
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Abstract

A new pyrrolopyrimidine alkaloid, rigidin E (1) and the known metabolites rigidin (2) and 1-methylherbipoline (3) have been isolated from a Papua New Guinea tunicate Eudistoma sp. A combination of spectroscopic data were used to determine the structures of these metabolites.
Keywords: Tunicate; Eudistoma sp.; rigidin E; cytotoxicity; HCT 116; A431 Tunicate; Eudistoma sp.; rigidin E; cytotoxicity; HCT 116; A431
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Davis, R.A.; Christensen, L.V.; Richardson, A.D.; Da Rocha, R.M.; Ireland, C.M. Rigidin E, a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species. Mar. Drugs 2003, 1, 27-33.

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