Hypertensive Emergency in Aortic Dissection and Thoracic Aortic Aneurysm—A Review of Management

doi:10.3390/ph2030066

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Pharmaceuticals 2009, 2(3), 66-76; doi:10.3390/ph2030066

Review

Hypertensive Emergency in Aortic Dissection and Thoracic Aortic Aneurysm—A Review of Management

Prateek K. Gupta, Himani Gupta and Ali Khoynezhad*

Division of Cardiothoracic and Vascular Surgery, Creighton University Medical Center, Omaha, NE 68131, USA

* Author to whom correspondence should be addressed.

Received: 10 August 2009; in revised form: 21 September 2009 / Accepted: 27 September 2009 / Published: 28 September 2009

(This article belongs to the Special Issue Antihypertensive Drugs)

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Abstract: Over the last few decades, treatment for aortic dissection and thoracic aortic aneurysms has evolved significantly with improvement in outcomes. Treatment paradigms include medical, endovascular and surgical options. As aortic dissection presents as a hypertensive emergency, diligent control of BP is of utmost importance in order to reduce the progression of dissection with possible aortic branch malperfusion. Treatment should begin on arrival to the emergency department and continues in the intensive care unit, endovascular suite or the operating room. Novel antihypertensive medications with improved pharmacological profile and improved surgical techniques, have improved the prognosis of patients with aortic aneurysm and/or aortic dissection. Nevertheless, morbidity and mortality remain high and hypertensive emergency poses a significant challenge in aortic dissection and thoracic aortic aneurysms.

Keywords: hypertension; emergency; aortic; aneurysm; dissection

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Cite This Article

MDPI and ACS Style

Gupta, P.K.; Gupta, H.; Khoynezhad, A. Hypertensive Emergency in Aortic Dissection and Thoracic Aortic Aneurysm—A Review of Management. Pharmaceuticals 2009, 2, 66-76.

AMA Style

Gupta PK, Gupta H, Khoynezhad A. Hypertensive Emergency in Aortic Dissection and Thoracic Aortic Aneurysm—A Review of Management. Pharmaceuticals. 2009; 2(3):66-76.

Chicago/Turabian Style

Gupta, Prateek K.; Gupta, Himani; Khoynezhad, Ali. 2009. "Hypertensive Emergency in Aortic Dissection and Thoracic Aortic Aneurysm—A Review of Management." Pharmaceuticals 2, no. 3: 66-76.

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