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Applications of Nanomaterials in Electrogenerated Chemiluminescence Biosensors
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Materials Science, Shaanxi Normal University, Xi’an, 710062, P. R. China
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Received: 31 October 2008; in revised form: 22 December 2008 / Accepted: 6 January 2009 / Published: 23 January 2009
Abstract: Electrogenerated chemiluminescence (also called electrochemiluminescence and abbreviated ECL) involves the generation of species at electrode surfaces that then undergo electron-transfer reactions to form excited states that emit light. ECL biosensor, combining advantages offered by the selectivity of the biological recognition elements and the sensitivity of ECL technique, is a powerful device for ultrasensitive biomolecule detection and quantification. Nanomaterials are of considerable interest in the biosensor field owing to their unique physical and chemical properties, which have led to novel biosensors that have exhibited high sensitivity and stability. Nanomaterials including nanoparticles and nanotubes, prepared from metals, semiconductor, carbon or polymeric species, have been widely investigated for their ability to enhance the efficiencies of ECL biosensors, such as taking as modification electrode materials, or as carrier of ECL labels and ECL-emitting species. Particularly useful application of nanomaterials in ECL biosensors with emphasis on the years 2004-2008 is reviewed. Remarks on application of nanomaterials in ECL biosensors are also surveyed.
Keywords: Electrogenerated Chemiluminescence; Nanomaterials; Biosensor; Amplification; Review
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MDPI and ACS Style
Qi, H.; Peng, Y.; Gao, Q.; Zhang, C. Applications of Nanomaterials in Electrogenerated Chemiluminescence Biosensors. Sensors 2009, 9, 674-695.
Qi H, Peng Y, Gao Q, Zhang C. Applications of Nanomaterials in Electrogenerated Chemiluminescence Biosensors. Sensors. 2009; 9(1):674-695.
Qi, Honglan; Peng, Yage; Gao, Qiang; Zhang, Chengxiao. 2009. "Applications of Nanomaterials in Electrogenerated Chemiluminescence Biosensors." Sensors 9, no. 1: 674-695.