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Sensors 2008, 8(2), 711-738; doi:10.3390/s8020711

Evanescent field Sensors Based on Tantalum Pentoxide Waveguides – A Review

1
Fraunhofer Institute for Physical Measurement Techniques, Heidenhofstr. 8, 79110 Freiburg, Germany
2
Institute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308 Heilbad Heiligenstadt, Germany
*
Author to whom correspondence should be addressed.
Received: 5 November 2007 / Accepted: 29 January 2008 / Published: 6 January 2008
(This article belongs to the Special Issue Optical Biosensors)
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Abstract

Evanescent field sensors based on waveguide surfaces play an important rolewhere high sensitivity is required. Particularly tantalum pentoxide (Ta2O5) is a suitablematerial for thin-film waveguides due to its high refractive index and low attenuation.Many label-free biosensor systems such as grating couplers and interferometric sensors aswell as fluorescence-based systems benefit from this waveguide material leading toextremely high sensitivity. Some biosensor systems based on Ta2O5 waveguides alreadytook the step into commercialization. This report reviews the various detection systems interms of limit of detection, the applications, and the suitable surface chemistry.
Keywords: biosensors; evanescent field; label-free detection; Ta2O5. biosensors; evanescent field; label-free detection; Ta2O5.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Schmitt, K.; Oehse, K.; Sulz, G.; Hoffmann, C. Evanescent field Sensors Based on Tantalum Pentoxide Waveguides – A Review. Sensors 2008, 8, 711-738.

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