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Surface Plasmon Spectroscopic Detection of Saxitoxin
College of Pharmacy, Pusan National University, Pusan 609-735, Korea
College of Nanoscience and Nanotechnology, Pusan National University, Pusan 609-735, Korea
College of Science and Technology, Jochiwon 339-700, Korea
College of Engineering, Kyungpook National University, Taegu 702-701, Korea
* Author to whom correspondence should be addressed.
Received: 18 June 2007; Accepted: 13 July 2007 / Published: 16 July 2007
Abstract: For the surface-optoelectronic study of Saxitoxin sensing, we fabricated self-assembled calixarene derivative monolayers as the recognition-functional interfaces ona gold surface. An interaction study between Saxitoxin and calixarene derivativemonolayers were performed using surface plasmon resonance (SPR) spectroscopy. Amongthree calixarene derivatives, calixarene crown ether SAM showed the highestsensitivity to Saxitoxin. The detection limit of this system is three orders of magnitudelower than that of the mouse bioassay which is the current benchmark for Saxitoxindetection.
Keywords: Saxitoxin; surface plasmon resonance; calixarene; self-assembled monolayer (SAM).
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Chen, H.; Kim, Y.S.; Keum, S.-R.; Kim, S.-H.; Choi, H.-J.; Lee, J.; An, W.G.; Koh, K. Surface Plasmon Spectroscopic Detection of Saxitoxin. Sensors 2007, 7, 1216-1223.
Chen H, Kim YS, Keum S-R, Kim S-H, Choi H-J, Lee J, An WG, Koh K. Surface Plasmon Spectroscopic Detection of Saxitoxin. Sensors. 2007; 7(7):1216-1223.
Chen, Hongxia; Kim, Youn S.; Keum, Sam-Rok; Kim, Sung-Hoon; Choi, Heung-Jin; Lee, Jaebeom; An, Won G.; Koh, Kwangnak. 2007. "Surface Plasmon Spectroscopic Detection of Saxitoxin." Sensors 7, no. 7: 1216-1223.