Sensors 2007, 7(4), 589-614; doi:10.3390/s7040589
Article

Biosensors and Bio-Bar Code Assays Based on Biofunctionalized Magnetic Microbeads

1,* email, 2email, 3email and 3email
Received: 5 March 2007; Accepted: 10 April 2007 / Published: 30 April 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: This review paper reports the applications of magnetic microbeads in biosensors and bio-bar code assays. Affinity biosensors are presented through different types of transducing systems: electrochemical, piezo electric or magnetic ones, applied to immunodetection and genodetection. Enzymatic biosensors are based on biofunctionalization through magnetic microbeads of a transducer, more often amperometric, potentiometric or conductimetric. The bio-bar code assays relie on a sandwich structure based on specific biological interaction of a magnetic microbead and a nanoparticle with a defined biological molecule. The magnetic particle allows the separation of the reacted target molecules from unreacted ones. The nanoparticles aim at the amplification and the detection of the target molecule. The bio-bar code assays allow the detection at very low concentration of biological molecules, similar to PCR sensitivity.
Keywords: Affinity Biosensors; Enzymatic Biosensors; Bio-Bar Code; Magnetic Microbeads
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MDPI and ACS Style

Jaffrezic-Renault, N.; Martelet, C.; Chevolot, Y.; Cloarec, J.-P. Biosensors and Bio-Bar Code Assays Based on Biofunctionalized Magnetic Microbeads. Sensors 2007, 7, 589-614.

AMA Style

Jaffrezic-Renault N, Martelet C, Chevolot Y, Cloarec J-P. Biosensors and Bio-Bar Code Assays Based on Biofunctionalized Magnetic Microbeads. Sensors. 2007; 7(4):589-614.

Chicago/Turabian Style

Jaffrezic-Renault, Nicole; Martelet, Claude; Chevolot, Yann; Cloarec, Jean-Pierre. 2007. "Biosensors and Bio-Bar Code Assays Based on Biofunctionalized Magnetic Microbeads." Sensors 7, no. 4: 589-614.

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