Sensors 2004, 4(1), 1-13; doi:10.3390/s40100001
Article

External Second Gate, Fourier Transform Ion Mobility Spectrometry: Parametric Optimization for Detection of Weapons of Mass Destruction

Sandia National Laboratories, Analytical Materials Sciences Department, P.O. Box 969, Mail Stop 9403, Livermore, CA 94551-0969, USA
Received: 2 May 2003; Accepted: 11 March 2004 / Published: 30 March 2004
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Abstract: Ion mobility spectrometry (IMS) is recognized as one of the most sensitive and robust techniques for the detection of narcotics, explosives and chemical warfare agents. IMS is widely used in forensic, military and security applications. Increasing threat of terrorist attacks, the proliferation of narcotics, Chemical Weapons Convention (CWC) treaty verification as well as humanitarian de-mining efforts have mandated that equal importance be placed on the time required to obtain results as well as the quality of the analytical data. [1] In this regard IMS is virtually unrivaled when both speed of response and sensitivity have to be considered. [2] The problem with conventional (signal averaging) IMS systems is the fixed duty cycle of the entrance gate that restricts to less than 1%, the number of available ions contributing to the measured signal. Furthermore, the signal averaging process incorporates scan-to-scan variations that degrade the spectral resolution contributing to misidentifications and false positives. With external second gate, Fourier Transform ion mobility spectrometry (FT-IMS) the entrance gate frequency is variable and can be altered in conjunction with other data acquisition parameters (scan time and sampling rate) to increase the spectral resolution to reduce false alarms and improve the sensitivity for early warning and contamination avoidance. In addition, with FT-IMS the entrance gate operates with a 50% duty cycle and so affords a seven-fold increase in sensitivity. Recent data on high explosives are presented to demonstrate the parametric optimization in sensitivity and resolution of our system.
Keywords: Ion mobility spectrometry; Fourier Transform ion mobility spectrometry; external second gate; Explosive samples

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MDPI and ACS Style

Tarver, E.E. External Second Gate, Fourier Transform Ion Mobility Spectrometry: Parametric Optimization for Detection of Weapons of Mass Destruction. Sensors 2004, 4, 1-13.

AMA Style

Tarver EE. External Second Gate, Fourier Transform Ion Mobility Spectrometry: Parametric Optimization for Detection of Weapons of Mass Destruction. Sensors. 2004; 4(1):1-13.

Chicago/Turabian Style

Tarver, Edward E. 2004. "External Second Gate, Fourier Transform Ion Mobility Spectrometry: Parametric Optimization for Detection of Weapons of Mass Destruction." Sensors 4, no. 1: 1-13.

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