Next Article in Journal
Corrosivity Sensor for Exposed Pipelines Based on Wireless Energy Transfer
Next Article in Special Issue
An NFC on Two-Coil WPT Link for Implantable Biomedical Sensors under Ultra-Weak Coupling
Previous Article in Journal
Using Color, Texture and Object-Based Image Analysis of Multi-Temporal Camera Data to Monitor Soil Aggregate Breakdown
Previous Article in Special Issue
Non-Invasive Fetal Monitoring: A Maternal Surface ECG Electrode Placement-Based Novel Approach for Optimization of Adaptive Filter Control Parameters Using the LMS and RLS Algorithms
Article Menu
Issue 6 (June) cover image

Export Article

Open AccessArticle
Sensors 2017, 17(6), 1245; doi:10.3390/s17061245

Smartphone-Based pH Sensor for Home Monitoring of Pulmonary Exacerbations in Cystic Fibrosis

1
Department of Electrical and Computer Engineering, University of California, San Diego, La Jolla, CA 92093, USA
2
Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Wan-Young Chung
Received: 10 April 2017 / Revised: 15 May 2017 / Accepted: 23 May 2017 / Published: 30 May 2017
(This article belongs to the Special Issue Biomedical Sensors and Systems 2017)
View Full-Text   |   Download PDF [2969 KB, uploaded 30 May 2017]   |  

Abstract

Currently, Cystic Fibrosis (CF) patients lack the ability to track their lung health at home, relying instead on doctor checkups leading to delayed treatment and lung damage. By leveraging the ubiquity of the smartphone to lower costs and increase portability, a smartphone-based peripheral pH measurement device was designed to attach directly to the headphone port to harvest power and communicate with a smartphone application. This platform was tested using prepared pH buffers and sputum samples from CF patients. The system matches within ~0.03 pH of a benchtop pH meter while fully powering itself and communicating with a Samsung Galaxy S3 smartphone paired with either a glass or Iridium Oxide (IrOx) electrode. The IrOx electrodes were found to have 25% higher sensitivity than the glass probes at the expense of larger drift and matrix sensitivity that can be addressed with proper calibration. The smartphone-based platform has been demonstrated as a portable replacement for laboratory pH meters, and supports both highly robust glass probes and the sensitive and miniature IrOx electrodes with calibration. This tool can enable more frequent pH sputum tracking for CF patients to help detect the onset of pulmonary exacerbation to provide timely and appropriate treatment before serious damage occurs. View Full-Text
Keywords: biosensor; Cystic Fibrosis; pH; point-of-care; smartphone; Iridium Oxide biosensor; Cystic Fibrosis; pH; point-of-care; smartphone; Iridium Oxide
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Sun, A.; Phelps, T.; Yao, C.; Venkatesh, A.G.; Conrad, D.; Hall, D.A. Smartphone-Based pH Sensor for Home Monitoring of Pulmonary Exacerbations in Cystic Fibrosis. Sensors 2017, 17, 1245.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top