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Sensors 2017, 17(6), 1200; doi:10.3390/s17061200

Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study

1
Eye Clinic Orasis, Swiss Eye Research Foundation, CH-5734 Reinach, Switzerland
2
Department of Physics, Faculty of Sciences, University of Novi Sad, 21000 Novi Sad, Serbia
3
Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, CH-1205 Geneva, Switzerland
4
Faculty of Medicine of the Military Medical Academy, University of Defence, 11000 Belgrade, Serbia
5
Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland
6
Department of Neurology, Schulthess Klinik, CH-8008 Zuerich, Switzerland
7
Optimo Medical, CH-2503 Biel, Switzerland
8
OCTlab, Department of Ophthalmology, University of Basel, CH-4001 Basel, Switzerland
*
Author to whom correspondence should be addressed.
Received: 31 March 2017 / Revised: 17 May 2017 / Accepted: 19 May 2017 / Published: 24 May 2017
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Abstract

Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corneal astigmatism. Results suggested that irradiation-induced pulling forces on the anterior corneal surface can cause astigmatism, as well as central corneal flattening. Finite element modeling of corneal biomechanics closely predicted the postoperative corneal surface (astigmatism error −0.01D; central curvature error −0.16D), and can help in understanding beta irradiation treatment. Numerical simulations have the potential to preoperatively predict corneal shape and function changes, and help to improve corneal treatments. View Full-Text
Keywords: pterygium; radiation; cornea surgery; biomechanics; finite element modeling; simulation pterygium; radiation; cornea surgery; biomechanics; finite element modeling; simulation
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MDPI and ACS Style

Pajic, B.; Aebersold, D.M.; Eggspuehler, A.; Theler, F.R.; Studer, H.P. Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study. Sensors 2017, 17, 1200.

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