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Sensors 2017, 17(12), 2771; https://doi.org/10.3390/s17122771

Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine

1
Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Korea
2
Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt
3
Department of Biomedical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Korea
*
Author to whom correspondence should be addressed.
Received: 13 October 2017 / Revised: 23 November 2017 / Accepted: 26 November 2017 / Published: 29 November 2017
(This article belongs to the Special Issue Carbon Materials Based Sensors and the Application)
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Abstract

Several neurological disorders such as Alzheimer’s disease and Parkinson’s disease have become a serious impediment to aging people nowadays. One of the efficient methods used to monitor these neurological disorders is the detection of neurotransmitters such as dopamine. Metal materials, such as gold and platinum, are widely used in this electrochemical detection method; however, low sensitivity and linearity at low dopamine concentrations limit the use of these materials. To overcome these limitations, a silver nanoparticle (SNP) modified electrode covered by graphene oxide for the detection of dopamine was newly developed in this study. For the first time, the surface of an indium tin oxide (ITO) electrode was modified using SNPs and graphene oxide sequentially through the electrochemical deposition method. The developed biosensor provided electrochemical signal enhancement at low dopamine concentrations in comparison with previous biosensors. Therefore, our newly developed SNP modified electrode covered by graphene oxide can be used to monitor neurological diseases through electrochemical signal enhancement at low dopamine concentrations. View Full-Text
Keywords: silver nanoparticle; neurotransmitter; dopamine; graphene oxide; electrochemical signal silver nanoparticle; neurotransmitter; dopamine; graphene oxide; electrochemical signal
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Shin, J.-W.; Kim, K.-J.; Yoon, J.; Jo, J.; El-Said, W.A.; Choi, J.-W. Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine. Sensors 2017, 17, 2771.

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