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Sensors 2016, 16(12), 2086; doi:10.3390/s16122086

A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection

Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China
Author to whom correspondence should be addressed.
Academic Editors: Giovanni Sparacino, Andrea Facchinetti and J. Hans DeVries
Received: 29 August 2016 / Revised: 31 October 2016 / Accepted: 2 November 2016 / Published: 8 December 2016
(This article belongs to the Special Issue Glucose Sensors: Revolution in Diabetes Management 2016)
View Full-Text   |   Download PDF [4868 KB, uploaded 8 December 2016]   |  


Glucose, as an essential substance directly involved in metabolic processes, is closely related to the occurrence of various diseases such as glucose metabolism disorders and islet cell carcinoma. Therefore, it is crucial to develop sensitive, accurate, rapid, and cost effective methods for frequent and convenient detections of glucose. Microfluidic Paper-based Analytical Devices (μPADs) not only satisfying the above requirements but also occupying the advantages of portability and minimal sample consumption, have exhibited great potential in the field of glucose detection. This article reviews and summarizes the most recent improvements in glucose detection in two aspects of colorimetric and electrochemical μPADs. The progressive techniques for fabricating channels on μPADs are also emphasized in this article. With the growth of diabetes and other glucose indication diseases in the underdeveloped and developing countries, low-cost and reliably commercial μPADs for glucose detection will be in unprecedentedly demand. View Full-Text
Keywords: microfluidic paper-based analytical devices (μPAD); glucose; colorimetric detection; electrochemical detection microfluidic paper-based analytical devices (μPAD); glucose; colorimetric detection; electrochemical detection

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Liu, S.; Su, W.; Ding, X. A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection. Sensors 2016, 16, 2086.

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