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Sensors 2015, 15(8), 20863-20872; doi:10.3390/s150820863

Lipid Multilayer Grating Arrays Integrated by Nanointaglio for Vapor Sensing by an Optical Nose

1
Department of Biological Science and Integrative Nanoscience Institute, Florida State University, 89 Chieftan Way, Tallahassee, FL 32304, USA
2
Department of Physics, Florida State University, 77 Chieftan Way, Tallahassee, FL 32304, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Montserrat Calleja
Received: 3 July 2015 / Revised: 29 July 2015 / Accepted: 17 August 2015 / Published: 21 August 2015
(This article belongs to the Special Issue Nanomechanics for Sensing and Spectrometry)
View Full-Text   |   Download PDF [722 KB, uploaded 24 August 2015]   |  

Abstract

Lipid multilayer gratings are recently invented nanomechanical sensor elements that are capable of transducing molecular binding to fluid lipid multilayers into optical signals in a label free manner due to shape changes in the lipid nanostructures. Here, we show that nanointaglio is suitable for the integration of chemically different lipid multilayer gratings into a sensor array capable of distinguishing vapors by means of an optical nose. Sensor arrays composed of six different lipid formulations are integrated onto a surface and their optical response to three different vapors (water, ethanol and acetone) in air as well as pH under water is monitored as a function of time. Principal component analysis of the array response results in distinct clustering indicating the suitability of the arrays for distinguishing these analytes. Importantly, the nanointaglio process used here is capable of producing lipid gratings out of different materials with sufficiently uniform heights for the fabrication of an optical nose. View Full-Text
Keywords: lipid; lipid multilayer; sensor; nanointaglio; nanofabrication; AFM; sensor-array; materials integration; microcontract printing; nanotechnology lipid; lipid multilayer; sensor; nanointaglio; nanofabrication; AFM; sensor-array; materials integration; microcontract printing; nanotechnology
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Lowry, T.W.; Prommapan, P.; Rainer, Q.; Van Winkle, D.; Lenhert, S. Lipid Multilayer Grating Arrays Integrated by Nanointaglio for Vapor Sensing by an Optical Nose. Sensors 2015, 15, 20863-20872.

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