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Sensors 2014, 14(8), 15496-15524; doi:10.3390/s140815496

Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk

1
INESC–MN—Instituto de Engenharia de Sistemas e Computadores–Microsistemas e Nanotecnologias and IN—Institute of Nanoscience and Nanotechnology, Rua Alves Redol 9, 1000-029 Lisbon, Portugal
2
CIISA, Veterinary Medicine Faculty, Technical University of Lisbon, Av. da Universidade Técnica, 1300-477 Lisbon, Portugal
3
Physics Department, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal
4
INL, International Iberian Nanotechnology Laboratory, Av.Mestre Jose Veiga, 4715-330 Braga, Portugal
*
Authors to whom correspondence should be addressed.
Received: 23 May 2014 / Revised: 14 July 2014 / Accepted: 1 August 2014 / Published: 21 August 2014
(This article belongs to the Special Issue Biomedical Sensors and Systems)

Abstract

Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk. View Full-Text
Keywords: cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Fernandes, A.C.; Duarte, C.M.; Cardoso, F.A.; Bexiga, R.; Cardoso, S.; Freitas, P.P. Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk. Sensors 2014, 14, 15496-15524.

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