Next Article in Journal
Wireless Laser Range Finder System for Vertical Displacement Monitoring of Mega-Trusses during Construction
Next Article in Special Issue
Biosensors in Clinical Practice: Focus on Oncohematology
Previous Article in Journal
A Split-Path Schema-Based RFID Data Storage Model in Supply Chain Management
Previous Article in Special Issue
Synthetic and Bio-Artificial Tactile Sensing: A Review
Article Menu

Export Article

Open AccessReview
Sensors 2013, 13(5), 5777-5795; doi:10.3390/s130505777

Microbial Biosensors: Engineered Microorganisms as the Sensing Machinery

1
Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA
2
Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan
*
Author to whom correspondence should be addressed.
Received: 11 March 2013 / Revised: 18 April 2013 / Accepted: 3 May 2013 / Published: 6 May 2013
(This article belongs to the Special Issue Live Cell-Based Sensors)
View Full-Text   |   Download PDF [1868 KB, uploaded 21 June 2014]   |  

Abstract

Whole-cell biosensors are a good alternative to enzyme-based biosensors since they offer the benefits of low cost and improved stability. In recent years, live cells have been employed as biosensors for a wide range of targets. In this review, we will focus on the use of microorganisms that are genetically modified with the desirable outputs in order to improve the biosensor performance. Different methodologies based on genetic/protein engineering and synthetic biology to construct microorganisms with the required signal outputs, sensitivity, and selectivity will be discussed.
Keywords: synthetic biology; scaffolds; genetic circuits synthetic biology; scaffolds; genetic circuits
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Park, M.; Tsai, S.-L.; Chen, W. Microbial Biosensors: Engineered Microorganisms as the Sensing Machinery. Sensors 2013, 13, 5777-5795.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top