Next Article in Journal
AURP: An AUV-Aided Underwater Routing Protocol for Underwater Acoustic Sensor Networks
Next Article in Special Issue
Gen-2 Hand-Held Optical Imager towards Cancer Imaging: Reflectance and Transillumination Phantom Studies
Previous Article in Journal
A Platform for Combined DNA and Protein Microarrays Based on Total Internal Reflection Fluorescence
Previous Article in Special Issue
Phantom with Pulsatile Arteries to Investigate the Influence of Blood Vessel Depth on Pulse Oximeter Signal Strength
Sensors 2012, 12(2), 1816-1826; doi:10.3390/s120201816
Article

Evaluation of Electrical and Optical Plethysmography Sensors for Noninvasive Monitoring of Hemoglobin Concentration

* ,
 and
Received: 14 December 2011; in revised form: 31 January 2012 / Accepted: 3 February 2012 / Published: 9 February 2012
(This article belongs to the Special Issue Optical Sensors in Medicine)
View Full-Text   |   Download PDF [924 KB, uploaded 21 June 2014]   |   Browse Figures
Abstract: Completely noninvasive monitoring of hemoglobin concentration has not yet been fully realized in the clinical setting. This study investigates the viability of measuring hemoglobin concentration noninvasively by evaluating the performance of two types of sensor using a tissue phantom perfused with a blood substitute. An electrical sensor designed to measure blood volume changes during the cardiac cycle was used together with an infrared optical sensor for detection of erythrocyte-bound hemoglobin. Both sensors demonstrated sensitivity to changes in pulse volume (plethysmography). The electrical sensor produced a signal referred to as capacitance plethysmograph (CPG) a quantity which was invariant to the concentration of an infrared absorbing dye present in the blood substitute. The optical sensor signal (photoplethysmograph) increased in amplitude with increasing absorber concentration. The ratio PPG:CPG is invariant to pulse pressure. This quantity is discussed as a possible index of in vivo hemoglobin concentration.
Keywords: hemoglobin; capacitance; plethysmography; noninvasive hemoglobin; capacitance; plethysmography; noninvasive
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Phillips, J.P.; Hickey, M.; Kyriacou, P.A. Evaluation of Electrical and Optical Plethysmography Sensors for Noninvasive Monitoring of Hemoglobin Concentration. Sensors 2012, 12, 1816-1826.

AMA Style

Phillips JP, Hickey M, Kyriacou PA. Evaluation of Electrical and Optical Plethysmography Sensors for Noninvasive Monitoring of Hemoglobin Concentration. Sensors. 2012; 12(2):1816-1826.

Chicago/Turabian Style

Phillips, Justin P.; Hickey, Michelle; Kyriacou, Panayiotis A. 2012. "Evaluation of Electrical and Optical Plethysmography Sensors for Noninvasive Monitoring of Hemoglobin Concentration." Sensors 12, no. 2: 1816-1826.


Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert