Responsive Hydrogels for Label-Free Signal Transduction within Biosensors
AbstractHydrogels have found wide application in biosensors due to their versatile nature. This family of materials is applied in biosensing either to increase the loading capacity compared to two-dimensional surfaces, or to support biospecific hydrogel swelling occurring subsequent to specific recognition of an analyte. This review focuses on various principles underpinning the design of biospecific hydrogels acting through various molecular mechanisms in transducing the recognition event of label-free analytes. Towards this end, we describe several promising hydrogel systems that when combined with the appropriate readout platform and quantitative approach could lead to future real-life applications.
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Gawel, K.; Barriet, D.; Sletmoen, M.; Stokke, B.T. Responsive Hydrogels for Label-Free Signal Transduction within Biosensors. Sensors 2010, 10, 4381-4409.
Gawel K, Barriet D, Sletmoen M, Stokke BT. Responsive Hydrogels for Label-Free Signal Transduction within Biosensors. Sensors. 2010; 10(5):4381-4409.Chicago/Turabian Style
Gawel, Kamila; Barriet, David; Sletmoen, Marit; Stokke, Bjørn Torger. 2010. "Responsive Hydrogels for Label-Free Signal Transduction within Biosensors." Sensors 10, no. 5: 4381-4409.