Abstract: A new design for microelectrode array (MEA) devices fabricated by semiconductor-processing techniques is presented. The microelectrode surfaces consist of gold and are surrounded by an insulating silicon nitride layer. Each chip of these so-called Multi MEAs contains regular arrays with circular-shaped electrodes of eight different sizes: 1, 3, 5, 10, 50, 100, 500 and 1000μm. The Multi MEAs were electrochemically characterised by use of ferrocenecarboxylic acid. Well-defined cyclic voltammograms of the two small redox proteins, horse heart cytochrome c and amicyanin from Thiobacillus versutus, were obtained at variously surface-modified Multi MEAs. Furthermore, a very simple method to manufacture Multi MEAs with carbon surfaces is introduced.
Keywords: Microelectrode array; bioelectrochemical sensor; direct protein electrochemistry; cytochrome c; amicyanin
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Kudera, M.; Hill, H.A.O.; Dobson, P.J.; Leigh, P.A.; McIntire, W.S. Electrochemical Characterisation and Application of Multi Microelectrode Array Devices to Biological Electrochemistry. Sensors 2001, 1, 18-28.
Kudera M, Hill HAO, Dobson PJ, Leigh PA, McIntire WS. Electrochemical Characterisation and Application of Multi Microelectrode Array Devices to Biological Electrochemistry. Sensors. 2001; 1(1):18-28.
Kudera, Michael; Hill, H. A.O.; Dobson, Peter J.; Leigh, Peter A.; McIntire, William S. 2001. "Electrochemical Characterisation and Application of Multi Microelectrode Array Devices to Biological Electrochemistry." Sensors 1, no. 1: 18-28.