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Diversity 2010, 2(3), 314-330; doi:10.3390/d2030314

Emerging Ranaviral Infectious Diseases and Amphibian Decline

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
Received: 1 December 2009 / Accepted: 25 February 2010 / Published: 26 February 2010
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Infectious diseases caused by ranaviruses (RV, family Iridoviridae) not only affect wild amphibian populations but also agriculture and international animal trade. Although, the prevalence of RV infections and die offs has markedly increased over the last decade, it is still unclear whether these viruses are direct causal agents of extinction or rather are the resulting (secondary) consequences of weakened health of amphibian populations leading to increased susceptibility to viral pathogens. In either case, it is important to understand the critical role of host immune defense in controlling RV infections, pathogenicity, and transmission; this is the focus of this review.
Keywords: viral immunity; Xenopus; Iridovirus viral immunity; Xenopus; Iridovirus
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Robert, J. Emerging Ranaviral Infectious Diseases and Amphibian Decline. Diversity 2010, 2, 314-330.

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