Next Article in Journal
Ethyl (E)-4-(2,4-Dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Previous Article in Journal
10a,11,11-Trimethyl-10a,11-dihydro-8H-benzo[e]imidazo[1,2-a]indol-9(10H)-one
Article Menu

Export Article

Open AccessShort Note
Molbank 2017, 2017(3), M945; doi:10.3390/M945

Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate

Department of Chemistry, Kyonggi University,154-42, Gwanggyosan-ro, Yeongtong-gu, Suwon 16227, Korea
*
Author to whom correspondence should be addressed.
Received: 30 June 2017 / Revised: 7 July 2017 / Accepted: 7 July 2017 / Published: 12 July 2017
(This article belongs to the Section Organic Synthesis)
View Full-Text   |   Download PDF [497 KB, uploaded 12 July 2017]   |  

Abstract

Ethyl 2-[2-(4-nitrobenzoyl)-1H-indol-3-yl]acetate was prepared in good yield and characterized by the aza-alkylation/intramolecular Michael cascade reaction of (E)-ethyl 3-[2-(tosylamino)phenyl]acrylate with 2-bromo-4′′-nitroacetophenone, followed by desulfonative dehydrogenation with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) The structure of the newly synthesized compound was determined using 1H-,13C-NMR, IR and mass spectral data. View Full-Text
Keywords: Indole; Michael reaction; dehydrogenation; cascade reaction Indole; Michael reaction; dehydrogenation; cascade reaction
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary materials

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Choi, S.; Kim, S.-G. Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate. Molbank 2017, 2017, M945.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top