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Molbank 2014, 2014(4), M836; doi:10.3390/M836

N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide

Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan
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Received: 6 August 2014 / Accepted: 23 October 2014 / Published: 28 October 2014
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Abstract

The title compound, N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin- 10(2H)-yl)ethylidene]-4-nitrobenzohydrazide (1), was obtained by the reaction of formylmethylflavin and p-nitrobenzohydrazide. The product 1 inhibited the DNA binding of nuclear factor-κB, and was characterized by 1H-NMR, 13C-NMR, electrospray ionization mass spectrometry, elemental analysis, IR and UV. View Full-Text
Keywords: flavin; Nuclear factor-κB; inhibitor; DNA binding flavin; Nuclear factor-κB; inhibitor; DNA binding
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Morikawa, M.; Kino, K.; Asada, E.; Katagiri, K.; Mori-Yasumoto, K.; Suzuki, M.; Kobayashi, T.; Miyazawa, H. N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide. Molbank 2014, 2014, M836.

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